Douglas Prado Ph.D.

PRADO, Douglas S.; CATTLEY, RICHARD T.; SHIPMAN, COREY W.; HAPPE, CASSANDRA; LEE, MIJOON; BOGGESS, WILLIAM C.; MACDONALD, MATTHEW L.; HAWSE, WILLIAM F. Synergistic and additive interactions between receptor signaling networks drive the regulatory T cell versus T helper 17 cell fate choice. Journal of Biological Chemistry, 2021

2.     PRADO, D.S.; DAMASCENO, L.E.A.; SONEGO, A.B.; ROSA, M.H.; ARTINS, T.V.;

FONSECA, M.D.M.; CUNHA, T.M.; CUNHA, F.Q.; ALVES-FILHO, J.C. Pitavastatin
ameliorates autoimmune neuroinflammation by regulating the Treg/Th17 cell balance
through inhibition of mevalonate metabolism. International Immunopharmacology, v. 91, p.1-10, 2021.

3.     PRADO, D.S.; VERAS, F. P.; FERREIRA, R. G.; DAMASCENO, L. E. A.; MELO, P. H.; ZAMBONI, DARIO S.; CUNHA, T. M.; CUNHA, F. Q.; ALVES-FILHO, J. C. NLRP12 controls arthritis severity by acting as a chekpoint inhibitor of Th17 cell differentiation. FASEB Journal, v. 34, p. 10907-10919, 2020.

4.     DAMASCENO, L. E. A.; PRADO, D.S.; VERAS, F. P.; FONSECA, M. D. M.; KAWAHISA, J.E.T.; ROSA, M. H.; PUBLIO, G. A.; MARTINS, T. V.; RAMALHO, F. S.; WAISMAN, A.; CUNHA, F.Q.; CUNHA, THIAGO M.; ALVES-FILHO, JOSE C. PKM2 promotesTh17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation. Journal of Experimental Medicine, v. 217, p. 1-16, 2020.

5.     LUIZ, JOÃO PAULO M.; TOLLER'KAWAHISA, JULIANA E.; VIACAVA, PAULA R.;
NASCIMENTO, DANIELE C.; PEREIRA, PRISCILLA T.; SARAIVA, ANDRÉ L.; PRADO,
Douglas S.; LEBERT, MARC; GIURISATO, EMANUELE; TOURNIER, CATHY; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; QUESNIAUX, VALERIE; RYFFEL, BERNHARD; ALVES-FILHO, JOSÉ C. MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression. Journal of Leukocyte Biology, v. 108, p.1215-1223, 2020.

6.     TAIRA, T.M.; LIMA, V.; PRADO, D.S.; SILVA, T.A.; ISSA, J.P.M.; DA SILVA, L.A.B.; ZAMBONI, D.S.; CUNHA, F.Q.; FUKADA, S.Y. NLRP12 Attenuates Inflammatory Bone Loss in Experimental Apical Periodontitis. Journal of Dental Research, v. 98, p. 476-484,2019.

7.      FERREIRA, RAPHAEL G.; RODRIGUES, LILIAN C.; NASCIMENTO, DANIELE C.; KANASHIRO, ALEXANDRE; MELO, PAULO H.; BORGES, VANESSA F.; GOZZI, ALINE; DA SILVA PRADO, DOUGLAS; BORGES, MARCOS C.; RAMALHO, FERNANDO S.; STOWELL, SEANR.; CUMMINGS, RICHARD D.; DIAS-BARUFFI, MARCELO; CUNHA, FERNANDO Q.; ALVES-FILHO, JOSE C. Galectin-3 aggravates experimental polymicrobial sepsis by impairing neutrophil recruitment to the infectious focus. Journal of Infection, v. 18, p.1-7, 2018.

8.     SONEGO, ANDREZA B.; PRADO, Douglas S.; VALE, GABRIEL T.; SEPULVEDA-DIAZ, JULIA E.; CUNHA, THIAGO M.; TIRAPELLI, CARLOS R.; DEL BEL, ELAINE A.; RAISMAN-VOZARI, RITA; GUIMARÃES, FRANCISCO S. Cannabidiol prevents haloperidol-inducedvacuoschewing movements and inflammatory changes in mice via PPARγreceptors. Brain, Behavior and Immunity, v. 74, p. 241-251, 2018.

9.     CAMPA, CARLO C.; SILVA, RANGEL L.; MARGARIA, JEAN P.; PIRALI, TRACEY; MATTOS, MATHEUS S.; KRAEMER, LUCAS R.; REIS, DIEGO C.; GROSA, GIORGIO; COPPERI, FRANCESCA; DALMARCO, EDUARDO M.; LIMA-JÚNIOR, ROBERTO C. P.; APRILE, SILVIO; SALA, VALENTINA; DAL BELLO, FEDERICA; PRADO, DOUGLAS SILVA; ALVES-FILHO, JOSE CARLOS; MEDANA, CLAUDIO; CASSALI, GEOVANNI D.; TRON, GIAN CESARE; TEIXEIRA, MAURO M.; CIRAOLO, ELISA; RUSSO, REMO C.; HIRSCH, EMILIO. Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis. Nature Communications, v. 9, p. 1-16, 2018.