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William Klimstra Publishes Two Papers

William Klimstra had a paper published in PLoS Pathogens demonstrating cooperativity between microRNA binding to sites in the eastern equine encephalitis virus 3’ untranslated region that leads to blockade of infection of immune sentinel cells and suppression of innate immune responses. Click here for that paper.

William had a second paper published in the Journal of Virology demonstrating that a subset of macrophages in vitro and in vivo are resistant to virus-induced macromolecular synthesis shutoff and produce interferon alpha/beta through an IRF-7 transcription factor dependent pathway. Click here for that paper.